Evaluation of Receptor Conversion and HER2 Discordance between Primary and Metastatic Breast Cancer and Predictive factors
نویسندگان
چکیده
Evaluation of Receptor Conversion and HER2 Discordance between Primary Metastatic Breast Cancer Predictive factors
منابع مشابه
Receptor status (ER, PgR and HER2) discordance between primary tumor and locoregional recurrence in breast cancer.
We report on three cases in which the HER2 status of a locoregional recurrence differed from that in the primary breast cancer. In one of these cases, estrogen receptor (ER) status also changed from primary to locoregional recurrence. All patients received neoadjuvant chemotherapy. Changes in HER2 and ER status between primary and metastatic breast cancer is a growing feature of the literature;...
متن کاملComparative study of receptor discordance between primary and corresponding metastatic lesions in breast cancer.
PURPOSE It is well-known that tumor phenotype may change during the progression of breast cancer (BC). The purpose in this study was to compare the discordance in estrogen receptor (ER), progesterone receptor (PgR) and human epidermal growth factor receptor 2 (HER2) between primary and recurrent/metastatic lesions (RML) and also to evaluate the prognostic significance of change in tumor phenoty...
متن کاملHER2 change between primary and metastatic breast cancer 1 HER2 PROTEIN AND GENE VARIATION BETWEEN PRIMARY AND METASTATIC BREAST CANCER: SIGNIFICANCE AND IMPACT ON PATIENT CARE
Purpose: To analyze HER2 status in primary breast cancer (BC) compared with correspondent metachronous metastases and to investigate whether BC phenotype may be predictive of change in HER2 expression. Experimental Design: HER2 was investigated by immunohistochemistry, silver (SISH) and fluorescent in situ hybridization (FISH), in a series of 137 tumors, building up a tissue microarray to concu...
متن کاملexamining the relationship between fear of negative evaluation and communication strategies by iranian efl learners
the purpose of the present study was to investigate the relationship between fear of negative evaluation (fne) and communication strategies (css) among iranian efl learners. it was aimed to examine the differences in the use of communication strategies between speakers with high or low degree of fear of negative evaluation. the current study was a case study consisting of 10 english learners at...
ذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ??????? ????????? ????? ?????
سال: 2022
ISSN: ['1735-9406', '2645-7482']
DOI: https://doi.org/10.30699/ijbd.15.4.4